JAK2(V617F) myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML

Interferon α (IFNα) is used to treat JAK2(V617F)-driven myeloproliferative neoplasms (MPNs) but rarely clears the disease. We investigated the IFNα mechanism of action focusing on PML, an interferon target and key senescence gene whose targeting by arsenic trioxide (ATO) drives eradication of acute...

詳細記述

保存先:
書誌詳細
出版年:J Exp Med
主要な著者: Dagher, Tracy, Maslah, Nabih, Edmond, Valérie, Cassinat, Bruno, Vainchenker, William, Giraudier, Stéphane, Pasquier, Florence, Verger, Emmanuelle, Niwa-Kawakita, Michiko, Lallemand-Breitenbach, Valérie, Plo, Isabelle, Kiladjian, Jean-Jacques, Villeval, Jean-Luc, de Thé, Hugues
フォーマット: Artigo
言語:Inglês
出版事項: Rockefeller University Press 2020
主題:
Brief Definitive Report
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7579737/
https://ncbi.nlm.nih.gov/pubmed/33075130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201268
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料