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Prediction of Protein Mutational Free Energy: Benchmark and Sampling Improvements Increase Classification Accuracy

Software to predict the change in protein stability upon point mutation is a valuable tool for a number of biotechnological and scientific problems. To facilitate the development of such software and provide easy access to the available experimental data, the ProTherm database was created. Biases in...

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Dades bibliogràfiques
Publicat a:Front Bioeng Biotechnol
Autors principals: Frenz, Brandon, Lewis, Steven M., King, Indigo, DiMaio, Frank, Park, Hahnbeom, Song, Yifan
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7579412/
https://ncbi.nlm.nih.gov/pubmed/33134287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.558247
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