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Microscopic Chromosomal Structural and Dynamical Origin of Cell Differentiation and Reprogramming

As an essential and fundamental process of life, cell development involves large‐scale reorganization of the 3D genome architecture, which forms the basis of gene regulation. Here, a landscape‐switching model is developed to explore the microscopic chromosomal structural origin of embryonic stem cel...

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Bibliografiske detaljer
Udgivet i:Adv Sci (Weinh)
Main Authors: Chu, Xiakun, Wang, Jin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578896/
https://ncbi.nlm.nih.gov/pubmed/33101859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202001572
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