Hypoxia-Induced Glioma-Derived Exosomal miRNA-199a-3p Promotes Ischemic Injury of Peritumoral Neurons by Inhibiting the mTOR Pathway

The underlying molecular mechanisms that the hypoxic microenvironment could aggravate neuronal injury are still not clear. In this study, we hypothesized that the exosomes, exosomal miRNAs, and the mTOR signaling pathway might be involved in hypoxic peritumoral neuronal injury in glioma. Multimodal...

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Dades bibliogràfiques
Publicat a:Oxid Med Cell Longev
Autors principals: Zhao, Jian-Lan, Tan, Bo, Chen, Gong, Che, Xiao-Ming, Du, Zhuo-Ying, Yuan, Qiang, Yu, Jian, Sun, Yi-Rui, Li, Xiao-Mu, Hu, Jin, Xie, Rong
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578720/
https://ncbi.nlm.nih.gov/pubmed/33110474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5609637
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