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Nrf2: A unifying transcription factor in the pathogenesis of Fuchs’ endothelial corneal dystrophy

Nuclear factor, erythroid 2 like 2 (Nrf2), is an oxidative stress induced transcription factor that regulates cytoprotective gene expression. Thus, Nrf2 is essential for cellular redox homeostasis. Loss or dysregulation of Nrf2 expression has been implicated in the pathogenesis of degenerative disea...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Lovatt, Matthew, Kocaba, Viridiana, Hui Neo, Dawn Jing, Soh, Yu Qiang, Mehta, Jodhbir S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578533/
https://ncbi.nlm.nih.gov/pubmed/33099215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101763
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