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Nrf2: A unifying transcription factor in the pathogenesis of Fuchs’ endothelial corneal dystrophy

Nuclear factor, erythroid 2 like 2 (Nrf2), is an oxidative stress induced transcription factor that regulates cytoprotective gene expression. Thus, Nrf2 is essential for cellular redox homeostasis. Loss or dysregulation of Nrf2 expression has been implicated in the pathogenesis of degenerative disea...

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Dades bibliogràfiques
Publicat a:Redox Biol
Autors principals: Lovatt, Matthew, Kocaba, Viridiana, Hui Neo, Dawn Jing, Soh, Yu Qiang, Mehta, Jodhbir S.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578533/
https://ncbi.nlm.nih.gov/pubmed/33099215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101763
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