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Nrf2: A unifying transcription factor in the pathogenesis of Fuchs’ endothelial corneal dystrophy

Nuclear factor, erythroid 2 like 2 (Nrf2), is an oxidative stress induced transcription factor that regulates cytoprotective gene expression. Thus, Nrf2 is essential for cellular redox homeostasis. Loss or dysregulation of Nrf2 expression has been implicated in the pathogenesis of degenerative disea...

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Bibliografiska uppgifter
I publikationen:Redox Biol
Huvudupphovsmän: Lovatt, Matthew, Kocaba, Viridiana, Hui Neo, Dawn Jing, Soh, Yu Qiang, Mehta, Jodhbir S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578533/
https://ncbi.nlm.nih.gov/pubmed/33099215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101763
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