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Overexpression of Mdm36 reveals Num1 foci that mediate dynein-dependent microtubule sliding in budding yeast

The current model for spindle positioning requires attachment of the microtubule (MT) motor cytoplasmic dynein to the cell cortex, where it generates pulling force on astral MTs to effect spindle displacement. How dynein is anchored by cortical attachment machinery to generate large spindle-pulling...

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Publicat a:J Cell Sci
Autors principals: Omer, Safia, Brock, Katia, Beckford, John, Lee, Wei-Lih
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578358/
https://ncbi.nlm.nih.gov/pubmed/32938686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.246363
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