Detection of EGFR Mutations in cfDNA and CTCs, and Comparison to Tumor Tissue in Non-Small-Cell-Lung-Cancer (NSCLC) Patients

Lung cancer is the leading cause of cancer-related mortality worldwide. Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) therapies, based on the evaluation of EGFR mutations, have shown dramatic clinical benefits. EGFR mutation assays are mainly performed on tumor biopsies, wh...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Liu, Haiyan E., Vuppalapaty, Meghah, Wilkerson, Charles, Renier, Corinne, Chiu, Michael, Lemaire, Clementine, Che, James, Matsumoto, Melissa, Carroll, James, Crouse, Steve, Hanft, Violet R., Jeffrey, Stefanie S., Di Carlo, Dino, Garon, Edward B., Goldman, Jonathan, Sollier, Elodie
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578230/
https://ncbi.nlm.nih.gov/pubmed/33117705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.572895
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