Clinical-grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning

BACKGROUND AND AIMS: Microsatellite instability (MSI) and mismatch-repair deficiency (dMMR) in colorectal tumors are used to select treatment for patients. Deep learning can detect MSI and dMMR in tumor samples on routine histology slides faster and cheaper than molecular assays. But clinical applic...

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Vydáno v:Gastroenterology
Hlavní autoři: Echle, Amelie, Grabsch, Heike Irmgard, Quirke, Philip, van den Brandt, Piet A., West, Nicholas P., Hutchins, Gordon G. A., Heij, Lara R., Tan, Xiuxiang, Richman, Susan D., Krause, Jeremias, Alwers, Elizabeth, Jenniskens, Josien, Offermans, Kelly, Gray, Richard, Brenner, Hermann, Chang-Claude, Jenny, Trautwein, Christian, Pearson, Alexander T., Boor, Peter, Luedde, Tom, Gaisa, Nadine Therese, Hoffmeister, Michael, Kather, Jakob Nikolas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578071/
https://ncbi.nlm.nih.gov/pubmed/32562722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.06.021
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