Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

Microsatellite instability determines whether patients with gastrointestinal cancer respond exceptionally well to immunotherapy. However, in clinical practice, not every patient is tested for MSI, because this requires additional genetic or immunohistochemical tests. Here we show that deep residual...

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izdano v:Nat Med
Main Authors: Kather, Jakob Nikolas, Pearson, Alexander T., Halama, Niels, Jäger, Dirk, Krause, Jeremias, Loosen, Sven H., Marx, Alexander, Boor, Peter, Tacke, Frank, Neumann, Ulf Peter, Grabsch, Heike I., Yoshikawa, Takaki, Brenner, Hermann, Chang-Claude, Jenny, Hoffmeister, Michael, Trautwein, Christian, Luedde, Tom
Format: Artigo
Jezik:Inglês
Izdano: 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423299/
https://ncbi.nlm.nih.gov/pubmed/31160815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-019-0462-y
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