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Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis

Chronic pancreatitis (CP) is associated with elevated plasma levels of bacterial lipopolysaccharide (LPS) and we have demonstrated reduced acinar cell autophagy in human CP tissue. Therefore, we investigated the role of autophagy in experimental endotoxin-induced pancreatic injury and aimed to ident...

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Detalles Bibliográficos
Publicado en:Cell Death Dis
Main Authors: Xia, L., Xu, Z., Zhou, X., Bergmann, F., Grabe, N., Büchler, M. W., Neoptolemos, J. P., Hackert, T., Kroemer, G., Fortunato, F.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578033/
https://ncbi.nlm.nih.gov/pubmed/33087696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03050-3
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