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Pharmacological methods to transcriptionally modulate double-strand break DNA repair

There is much interest in targeting DNA repair pathways for use in cancer therapy, as the effectiveness of many therapeutic agents relies on their ability to cause damage to DNA, and deficiencies in DSB repair pathways can make cells more sensitive to specific cancer therapies. For example, defects...

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Detaylı Bibliyografya
Yayımlandı:Int Rev Cell Mol Biol
Asıl Yazarlar: Kaplan, Alanna R., Glazer, Peter M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577782/
https://ncbi.nlm.nih.gov/pubmed/32475473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.ircmb.2019.11.003
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