Matrix metalloproteinase-degraded type I collagen is associated with APOE/TOMM40 variants and preclinical dementia

OBJECTIVE: Dysregulation of type I collagen metabolism has a great impact on human health. We have previously seen that matrix metalloproteinase–degraded type I collagen (C1M) is associated with early death and age-related pathologies. To dissect the biological impact of type I collagen dysregulatio...

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Veröffentlicht in:Neurol Genet
Hauptverfasser: Tang, Man-Hung Eric, Blair, Joseph P.M., Bager, Cecilie Liv, Bay-Jensen, Anne-Christine, Henriksen, Kim, Christiansen, Claus, Karsdal, Morten Asser
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577557/
https://ncbi.nlm.nih.gov/pubmed/33134509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000508
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