Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms: A Genetic Correlation and 2-Sample Mendelian Randomization Study

IMPORTANCE: Observational studies highlight associations of C-reactive protein (CRP), a general marker of inflammation, and interleukin 6 (IL-6), a cytokine-stimulating CRP production, with individual depressive symptoms. However, it is unclear whether inflammatory activity is associated with indivi...

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Detalhes bibliográficos
Publicado no:JAMA Psychiatry
Main Authors: Kappelmann, Nils, Arloth, Janine, Georgakis, Marios K., Czamara, Darina, Rost, Nicolas, Ligthart, Symen, Khandaker, Golam M., Binder, Elisabeth B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2020
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577200/
https://ncbi.nlm.nih.gov/pubmed/33079133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2020.3436
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