Ribosome-Mediated Attenuation of vga(A) Expression Is Shaped by the Antibiotic Resistance Specificity of Vga(A) Protein Variants

Vga(A) protein variants confer different levels of resistance to lincosamides, streptogramin A, and pleuromutilins (LS(A)P) by displacing antibiotics from the ribosome. Here, we show that expression of vga(A) variants from Staphylococcus haemolyticus is regulated by cis-regulatory RNA in response to...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Vimberg, Vladimir, Cavanagh, Jorunn Pauline, Novotna, Michaela, Lenart, Jakub, Nguyen Thi Ngoc, Bich, Vesela, Jana, Pain, Maria, Koberska, Marketa, Balikova Novotna, Gabriela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577164/
https://ncbi.nlm.nih.gov/pubmed/32816732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00666-20
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