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In Vivo Activity of QPX7728, an Ultrabroad-Spectrum Beta-Lactamase Inhibitor, in Combination with Beta-Lactams against Carbapenem-Resistant Klebsiella pneumoniae

Resistance to beta-lactams has created a major clinical issue. QPX7728 is a novel ultrabroad-spectrum cyclic boronic acid beta-lactamase inhibitor with activity against both serine and metallo-beta-lactamases developed to address this resistance for use in combination with beta-lactam antibiotics. T...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Sabet, Mojgan, Tarazi, Ziad, Griffith, David C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577155/
https://ncbi.nlm.nih.gov/pubmed/32839224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01267-20
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