Population Pharmacodynamic Modeling of Epoetin Alfa in End‐Stage Renal Disease Patients Receiving Maintenance Treatment Using Bayesian Approach

The ability to control dosage regimens of erythropoiesis‐stimulating agents (ESAs) to maintain a desired hemoglobin (HGB) target is still elusive. We utilized a Bayesian approach and informative priors to characterize HGB profiles, using simulated drug concentrations, in patients with end‐stage rena...

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Vydáno v:CPT Pharmacometrics Syst Pharmacol
Hlavní autoři: Nguyen, Ly Minh, Meaney, Calvin J., Rao, Gauri G., Panesar, Mandip, Krzyzanski, Wojciech
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577019/
https://ncbi.nlm.nih.gov/pubmed/32996284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12556
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