Valproic acid inhibits interferon-γ production by NK cells and increases susceptibility to Listeria monocytogenes infection

Valproic acid (VPA) is a drug commonly used for epileptic seizure control. Recently, it has been shown that VPA alters the activation of several immune cells, including Natural Killer (NK) cells, which play an important role in the containment of viruses and intracellular bacteria. Although VPA can...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Soria-Castro, Rodolfo, Chávez-Blanco, Alma D., García-Pérez, Blanca Estela, Wong-Baeza, Isabel, Flores-Mejía, Raúl, Flores-Borja, Fabián, Estrada-Parra, Sergio, Estrada-García, Iris, Serafín-López, Jeanet, Chacón-Salinas, Rommel
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576816/
https://ncbi.nlm.nih.gov/pubmed/33082490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74836-w
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