Valproic acid inhibits interferon-γ production by NK cells and increases susceptibility to Listeria monocytogenes infection

Valproic acid (VPA) is a drug commonly used for epileptic seizure control. Recently, it has been shown that VPA alters the activation of several immune cells, including Natural Killer (NK) cells, which play an important role in the containment of viruses and intracellular bacteria. Although VPA can...

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Publicat a:Sci Rep
Autors principals: Soria-Castro, Rodolfo, Chávez-Blanco, Alma D., García-Pérez, Blanca Estela, Wong-Baeza, Isabel, Flores-Mejía, Raúl, Flores-Borja, Fabián, Estrada-Parra, Sergio, Estrada-García, Iris, Serafín-López, Jeanet, Chacón-Salinas, Rommel
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576816/
https://ncbi.nlm.nih.gov/pubmed/33082490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74836-w
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