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Valproic acid inhibits interferon-γ production by NK cells and increases susceptibility to Listeria monocytogenes infection

Valproic acid (VPA) is a drug commonly used for epileptic seizure control. Recently, it has been shown that VPA alters the activation of several immune cells, including Natural Killer (NK) cells, which play an important role in the containment of viruses and intracellular bacteria. Although VPA can...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Soria-Castro, Rodolfo, Chávez-Blanco, Alma D., García-Pérez, Blanca Estela, Wong-Baeza, Isabel, Flores-Mejía, Raúl, Flores-Borja, Fabián, Estrada-Parra, Sergio, Estrada-García, Iris, Serafín-López, Jeanet, Chacón-Salinas, Rommel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576816/
https://ncbi.nlm.nih.gov/pubmed/33082490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74836-w
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