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Exposure–response relationships of dapagliflozin on cardiorenal risk markers and adverse events: A pooled analysis of 13 phase II/III trials

AIMS: Dapagliflozin is a sodium–glucose co‐transporter 2 inhibitor that has been developed as oral glucose lowering drug. The original dosefinding studies focused on optimal glycaemic effects. However, dapagliflozin also affects various cardiorenal risk markers and provides cardiorenal protection. T...

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Bibliographic Details
Published in:Br J Clin Pharmacol
Main Authors: Koomen, Jeroen V., Stevens, Jasper, Heerspink, Hiddo J.L.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576615/
https://ncbi.nlm.nih.gov/pubmed/32311110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14318
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