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Exposure–response relationships of dapagliflozin on cardiorenal risk markers and adverse events: A pooled analysis of 13 phase II/III trials

AIMS: Dapagliflozin is a sodium–glucose co‐transporter 2 inhibitor that has been developed as oral glucose lowering drug. The original dosefinding studies focused on optimal glycaemic effects. However, dapagliflozin also affects various cardiorenal risk markers and provides cardiorenal protection. T...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Koomen, Jeroen V., Stevens, Jasper, Heerspink, Hiddo J.L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576615/
https://ncbi.nlm.nih.gov/pubmed/32311110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14318
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