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Targeting c-Myc with a novel Peptide Nuclear Delivery Device

Biologics such as peptides and antibodies are a well-established class of therapeutics. However, their intracellular delivery remains problematic. In particular, methods to efficiently inhibit intra-nuclear targets are lacking. We previously described that Pseudomonas Exotoxin A reaches the nucleopl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ting, Trinda Anne, Chaumet, Alexandre, Bard, Frederic Andre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576588/
https://ncbi.nlm.nih.gov/pubmed/33082422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73998-x
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