A Computational Approach for Defining a Signature of β-Cell Golgi Stress in Diabetes

The Golgi apparatus (GA) is an important site of insulin processing and granule maturation, but whether GA organelle dysfunction and GA stress are present in the diabetic β-cell has not been tested. We used an informatics-based approach to develop a transcriptional signature of β-cell GA stress usin...

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Detaylı Bibliyografya
Yayımlandı:Diabetes
Asıl Yazarlar: Bone, Robert N., Oyebamiji, Olufunmilola, Talware, Sayali, Selvaraj, Sharmila, Krishnan, Preethi, Syed, Farooq, Wu, Huanmei, Evans-Molina, Carmella
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2020
Konular:
Islet Studies
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576569/
https://ncbi.nlm.nih.gov/pubmed/32820009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0636
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