Phillyrin Mitigates Apoptosis and Oxidative Stress in Hydrogen Peroxide-Treated RPE Cells through Activation of the Nrf2 Signaling Pathway

Oxidative stress-induced dysfunction or apoptosis in retinal pigment epithelial (RPE) cells is an important cause of dry age-related macular degeneration (AMD). Although phillyrin has been shown to exert significant antioxidant effects, the underlying mechanism of action remains unclear. The purpose...

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Udgivet i:Oxid Med Cell Longev
Main Authors: Du, Yuanyuan, You, Longtai, Ni, Boran, Sai, Na, Wang, Wenping, Sun, Mingyi, Xu, Rui, Yao, Yu, Zhang, Zhiqin, Qu, Changhai, Yin, Xingbin, Ni, Jian
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2020
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576358/
https://ncbi.nlm.nih.gov/pubmed/33101585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2684672
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