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Extracellular adenosine signaling reverses the age‐driven decline in the ability of neutrophils to kill Streptococcus pneumoniae

The elderly are susceptible to serious infections by Streptococcus pneumoniae (pneumococcus), which calls for a better understanding of the pathways driving the decline in host defense in aging. We previously found that extracellular adenosine (EAD) shaped polymorphonuclear cell (PMN) responses, whi...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Bhalla, Manmeet, Simmons, Shaunna R., Abamonte, Alexsandra, Herring, Sydney E., Roggensack, Sara E., Bou Ghanem, Elsa N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576260/
https://ncbi.nlm.nih.gov/pubmed/32790148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13218
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