Extracellular Adenosine Protects against Streptococcus pneumoniae Lung Infection by Regulating Pulmonary Neutrophil Recruitment

An important determinant of disease following Streptococcus pneumoniae (pneumococcus) lung infection is pulmonary inflammation mediated by polymorphonuclear leukocytes (PMNs). We found that upon intratracheal challenge of mice, recruitment of PMNs into the lungs within the first 3 hours coincided wi...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Bou Ghanem, Elsa N., Clark, Stacie, Roggensack, Sara E., McIver, Sally R., Alcaide, Pilar, Haydon, Philip G., Leong, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552087/
https://ncbi.nlm.nih.gov/pubmed/26313746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005126
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