Extracellular Adenosine Protects against Streptococcus pneumoniae Lung Infection by Regulating Pulmonary Neutrophil Recruitment

An important determinant of disease following Streptococcus pneumoniae (pneumococcus) lung infection is pulmonary inflammation mediated by polymorphonuclear leukocytes (PMNs). We found that upon intratracheal challenge of mice, recruitment of PMNs into the lungs within the first 3 hours coincided wi...

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Publicat a:PLoS Pathog
Autors principals: Bou Ghanem, Elsa N., Clark, Stacie, Roggensack, Sara E., McIver, Sally R., Alcaide, Pilar, Haydon, Philip G., Leong, John M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552087/
https://ncbi.nlm.nih.gov/pubmed/26313746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005126
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