Extracellular Adenosine Protects against Streptococcus pneumoniae Lung Infection by Regulating Pulmonary Neutrophil Recruitment

An important determinant of disease following Streptococcus pneumoniae (pneumococcus) lung infection is pulmonary inflammation mediated by polymorphonuclear leukocytes (PMNs). We found that upon intratracheal challenge of mice, recruitment of PMNs into the lungs within the first 3 hours coincided wi...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Bou Ghanem, Elsa N., Clark, Stacie, Roggensack, Sara E., McIver, Sally R., Alcaide, Pilar, Haydon, Philip G., Leong, John M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552087/
https://ncbi.nlm.nih.gov/pubmed/26313746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005126
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