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Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery

A key component of cardiac ischemia–reperfusion injury (IRI) is the increased generation of reactive oxygen species, leading to enhanced inflammation and tissue dysfunction in patients following intervention for myocardial infarction. In this study, we hypothesized that oxidative stress, due to isch...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Dookun, Emily, Walaszczyk, Anna, Redgrave, Rachael, Palmowski, Pawel, Tual‐Chalot, Simon, Suwana, Averina, Chapman, James, Jirkovsky, Eduard, Donastorg Sosa, Leticia, Gill, Eleanor, Yausep, Oliver E, Santin, Yohan, Mialet‐Perez, Jeanne, Andrew Owens, W, Grieve, David, Spyridopoulos, Ioakim, Taggart, Michael, Arthur, Helen M., Passos, João F., Richardson, Gavin D.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576252/
https://ncbi.nlm.nih.gov/pubmed/32996233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13249
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