GNAS mutation detection in circulating cell-free DNA is a specific predictor for intraductal papillary mucinous neoplasms of the pancreas, especially for intestinal subtype

Pancreatic cystic neoplasms (PCNs) are a heterogeneous group with varying risks of malignancy. To explore the clinical utility of liquid biopsy in cyst type classification, we analyzed the GNAS/KRAS mutations in circulating cell-free DNA (cfDNA) obtained from 57 patients with histologically diagnose...

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Publicado en:Sci Rep
Main Authors: Hata, Tatsuo, Mizuma, Masamichi, Motoi, Fuyuhiko, Omori, Yuko, Ishida, Masaharu, Nakagawa, Kei, Hayashi, Hiroki, Morikawa, Takanori, Kamei, Takashi, Furukawa, Toru, Unno, Michiaki
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576136/
https://ncbi.nlm.nih.gov/pubmed/33082481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74868-2
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