Delay in articular cartilage degeneration of the knee joint by the conditional removal of discoidin domain receptor 2 in a spontaneous mouse model of osteoarthritis

BACKGROUND: Discoidin domain receptor 2 (Ddr2) is a rate-limiting factor in articular cartilage degeneration, a condition which normally leads to joint destruction. In human osteoarthritic tissues and mouse models of osteoarthritis (OA), the expression of Ddr2 increases and interacts with collagen t...

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Опубликовано в: :Ann Transl Med
Главные авторы: Li, Xiaolong, Chen, Yi, Xu, Rui, Wang, Yan, Jian, Fan, Long, Hu, Lai, Wenli
Формат: Artigo
Язык:Inglês
Опубликовано: AME Publishing Company 2020
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576030/
https://ncbi.nlm.nih.gov/pubmed/33241027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5786
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