Inhibition of formyl peptide receptor 1 activity suppresses tumorigenicity in vivo and attenuates the invasion and migration of lung adenocarcinoma cells under hypoxic conditions in vitro

BACKGROUND: Tumor hypoxia has been widely reported to promote metastasis. However, the molecular mechanisms underlying metastasis-associated hypoxia remain unclear. Formyl peptide receptor 1 (FPR1) has been reported to be highly expressed under hypoxic conditions. This study aimed to explore the rol...

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Bibliografiska uppgifter
I publikationen:Ann Transl Med
Huvudupphovsmän: Huang, Bo, Guo, Hongrong, Ding, Jie, Li, Jun, Wang, Hongjuan, Xu, Jianqun, Zheng, Quan, Zhou, Lijun, Dai, Qin
Materialtyp: Artigo
Språk:Inglês
Publicerad: AME Publishing Company 2020
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576028/
https://ncbi.nlm.nih.gov/pubmed/33241023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5864
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