Metformin suppresses lung adenocarcinoma by downregulating long non-coding RNA (lncRNA) AFAP1-AS1 and secreted phosphoprotein 1 (SPP1) while upregulating miR-3163

AFAP1-AS1 plays a pro-tumor role in lung cancer. However, no investigation has focused on whether it is involved in the anticancer activity of metformin (Met) in the treatment of lung adenocarcinoma (LUAD). Reverse transcription quantitative polymerase chain reaction (RT-qPCR) was performed to detec...

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Библиографические подробности
Главные авторы: Caiyu Qiu, Chuanxiang Li, Quan Zheng, Si Fang, Jianqun Xu, Hongjuan Wang, Hongrong Guo
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis Group 2022-05-01
Серии:Bioengineered
Предметы:
Metformin
lncRNA AFAP1-AS1
miR-3163
SPP1 lung adenocarcinoma
Online-ссылка:https://www.tandfonline.com/doi/10.1080/21655979.2021.2005981
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