Sonic Hedgehog Signaling in Cranial Neural Crest Cells Regulates Microvascular Morphogenesis in Facial Development

Sonic hedgehog (Shh) pathway disruption causes craniofacial malformations including orofacial clefts (OFCs) of the lip and palate. In normal craniofacial morphogenesis, Shh signals to multipotent cranial neural crest cells (cNCCs) and was recently discovered to regulate the angiogenic transcriptome,...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Main Authors: Sun, Miranda R., Chung, Hannah M., Matsuk, Veronika, Fink, Dustin M., Stebbins, Matthew J., Palecek, Sean P., Shusta, Eric V., Lipinski, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575766/
https://ncbi.nlm.nih.gov/pubmed/33117819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.590539
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