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Neuron type-specific expression of a mutant KRAS impairs hippocampal-dependent learning and memory
KRAS mutations are associated with rare cases of neurodevelopmental disorders that can cause intellectual disabilities. Previous studies showed that mice expressing a mutant KRAS have impaired the development and function of GABAergic inhibitory neurons, which may contribute to behavioural deficits...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7575532/ https://ncbi.nlm.nih.gov/pubmed/33082413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74610-y |
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