Φορτώνει......
Dynamics-Based Discovery of Allosteric Inhibitors: Selection of New Ligands for the C-terminal Domain of Hsp90
The study of allosteric functional modulation in dynamic proteins is attracting increasing attention. In particular, the discovery of new allosteric sites may generate novel opportunities and strategies for drug development, overcoming the limits of classical active-site oriented drug design. In thi...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Chem Theory Comput |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7575213/ https://ncbi.nlm.nih.gov/pubmed/26616092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct100334n |
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