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Luminespib counteracts the Kifunensine-induced lung endothelial barrier dysfunction

Unfolded protein response (UPR) suppression by Kifunensine has been associated with lung hyperpermeability, the hallmark of Acute Respiratory Distress Syndrome. The present study investigates the effects of the heat shock protein 90 inhibitor Luminespib (AUY-922) towards the Kifunensine-triggered lu...

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Bibliographic Details
Published in:Curr Res Toxicol
Main Authors: Kubra, Khadeja-Tul, Uddin, Mohammad A., Akhter, Mohammad S., Barabutis, Nektarios
Format: Artigo
Language:Inglês
Published: Elsevier 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575137/
https://ncbi.nlm.nih.gov/pubmed/33094291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crtox.2020.09.003
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