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Poxvirus-encoded decapping enzymes promote selective translation of viral mRNAs
Cellular decapping enzymes negatively regulate gene expression by removing the methylguanosine cap at the 5’ end of eukaryotic mRNA, rendering mRNA susceptible to degradation and repressing mRNA translation. Vaccinia virus (VACV), the prototype poxvirus, encodes two decapping enzymes, D9 and D10, th...
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| Publicat a: | PLoS Pathog |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7575113/ https://ncbi.nlm.nih.gov/pubmed/33031446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008926 |
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