Ribosome Profiling Reveals Translational Upregulation of Cellular Oxidative Phosphorylation mRNAs during Vaccinia Virus-Induced Host Shutoff

Vaccinia virus infection causes a host shutoff that is marked by global inhibition of host protein synthesis. Though the host shutoff may facilitate reallocation of cellular resources for viral replication and evasion of host antiviral immune responses, it poses a challenge for continuous synthesis...

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Bibliographic Details
Published in:J Virol
Main Authors: Dai, Aimei, Cao, Shuai, Dhungel, Pragyesh, Luan, Yizhao, Liu, Yizhi, Xie, Zhi, Yang, Zhilong
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309933/
https://ncbi.nlm.nih.gov/pubmed/28003488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01858-16
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