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Phosphorylation of eIF2α Promotes Schwann Cell Differentiation and Myelination in CMT1B Mice with Activated UPR

Myelin Protein Zero (MPZ/P0) is the most abundant glycoprotein of peripheral nerve myelin. P0 is synthesized by myelinating Schwann cells, processed in the endoplasmic reticulum (ER) and delivered to myelin via the secretory pathway. The mutant P0S63del (deletion of serine 63 in the extracellular do...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Scapin, Cristina, Ferri, Cinzia, Pettinato, Emanuela, Bianchi, Francesca, Del Carro, Ubaldo, Feltri, M. Laura, Kaufman, Randal J., Wrabetz, Lawrence, D'Antonio, Maurizio
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574653/
https://ncbi.nlm.nih.gov/pubmed/32973043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0957-20.2020
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