Exploration of the sputum methylome and omics deconvolution by quadratic programming in molecular profiling of asthma and COPD: the road to sputum omics 2.0

BACKGROUND: To date, most studies involving high-throughput analyses of sputum in asthma and COPD have focused on identifying transcriptomic signatures of disease. No whole-genome methylation analysis of sputum cells has been performed yet. In this context, the highly variable cellular composition o...

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Dettagli Bibliografici
Pubblicato in:Respir Res
Autori principali: Groth, Espen E., Weber, Melanie, Bahmer, Thomas, Pedersen, Frauke, Kirsten, Anne, Börnigen, Daniela, Rabe, Klaus F., Watz, Henrik, Ammerpohl, Ole, Goldmann, Torsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574293/
https://ncbi.nlm.nih.gov/pubmed/33076907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-01544-4
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