Association of Initial β-Amyloid Levels With Subsequent Flortaucipir Positron Emission Tomography Changes in Persons Without Cognitive Impairment

IMPORTANCE: Tau accumulation in Alzheimer disease (AD) is closely associated with cognitive impairment. Quantitating tau accumulation by positron emission tomography (PET) will be a useful outcome measure for future clinical trials in the AD spectrum. OBJECTIVE: To investigate the association of β-a...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Knopman, David S., Lundt, Emily S., Therneau, Terry M., Albertson, Sabrina M., Gunter, Jeffrey L., Senjem, Matthew L., Schwarz, Christopher G., Mielke, Michelle M., Machulda, Mary M., Boeve, Bradley F., Jones, David T., Graff-Radford, Jon, Vemuri, Prashanthi, Kantarci, Kejal, Lowe, Val J., Petersen, Ronald C., Jack, Clifford R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2020
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573795/
https://ncbi.nlm.nih.gov/pubmed/33074304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2020.3921
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