Role of β-amyloidosis and Neurodegeneration in Subsequent Imaging Changes in Mild Cognitive Impairment

IMPORTANCE: To understand how a model of Alzheimer disease pathophysiology based on β-amyloidosis and neurodegeneration predicts the regional anatomic expansion of hypometabolism and atrophy in persons with mild cognitive impairment (MCI). OBJECTIVE: To define the role of β-amyloidosis and neurodege...

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Udgivet i:JAMA Neurol
Main Authors: Knopman, David S., Jack, Clifford R., Lundt, Emily S., Wiste, Heather J., Weigand, Stephen D., Vemuri, Prashanthi, Lowe, Val J., Kantarci, Kejal, Gunter, Jeffrey L., Senjem, Matthew L., Mielke, Michelle M., Machulda, Mary M., Roberts, Rosebud O., Boeve, Bradley F., Jones, David T., Petersen, Ronald C.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735877/
https://ncbi.nlm.nih.gov/pubmed/26437123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2015.2323
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