Role of β-amyloidosis and Neurodegeneration in Subsequent Imaging Changes in Mild Cognitive Impairment

IMPORTANCE: To understand how a model of Alzheimer disease pathophysiology based on β-amyloidosis and neurodegeneration predicts the regional anatomic expansion of hypometabolism and atrophy in persons with mild cognitive impairment (MCI). OBJECTIVE: To define the role of β-amyloidosis and neurodege...

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Publicado en:JAMA Neurol
Autores principales: Knopman, David S., Jack, Clifford R., Lundt, Emily S., Wiste, Heather J., Weigand, Stephen D., Vemuri, Prashanthi, Lowe, Val J., Kantarci, Kejal, Gunter, Jeffrey L., Senjem, Matthew L., Mielke, Michelle M., Machulda, Mary M., Roberts, Rosebud O., Boeve, Bradley F., Jones, David T., Petersen, Ronald C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735877/
https://ncbi.nlm.nih.gov/pubmed/26437123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2015.2323
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