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Exploring polar headgroup interactions between sphingomyelin and ceramide with infrared spectroscopy

Ceramide is a major actor in the sphingolipid signaling pathway elicited by various kinds of cell stress. Under those conditions ceramide (Cer) is produced in the plasma membrane as a product of sphingomyelin (SM) hydrolysis, and this may lead to apoptosis. Thus, SM and Cer coexist in the membrane f...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: de la Arada, Igor, González-Ramírez, Emilio J., Alonso, Alicia, Goñi, Félix M., Arrondo, José-Luis R.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573612/
https://ncbi.nlm.nih.gov/pubmed/33077787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74781-8
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