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HIF1α is not a target of 14q deletion in clear cell renal cancer

HIF1α has been termed a tumor-suppressor in clear cell renal cell carcinoma (ccRCC), primarily based on functional proliferation studies in cell lines (in vitro and in vivo) with genetic manipulation, and the adverse prognosis of 14q-deleted ccRCC patients. In other malignancies, however, HIF1α has...

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Detalhes bibliográficos
Publicado no:Sci Rep
Autor principal: Shenoy, Niraj
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573601/
https://ncbi.nlm.nih.gov/pubmed/33077781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74631-7
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