Three-Dimensional In Vitro Staphylococcus aureus Abscess Communities Display Antibiotic Tolerance and Protection from Neutrophil Clearance

Staphylococcus aureus is a prominent human pathogen in bone and soft-tissue infections. Pathophysiology involves abscess formation, which consists of central staphylococcal abscess communities (SACs), surrounded by a fibrin pseudocapsule and infiltrating immune cells. Protection against the ingress...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Hofstee, Marloes I., Riool, Martijn, Terjajevs, Igors, Thompson, Keith, Stoddart, Martin J., Richards, R. Geoff, Zaat, Sebastian A. J., Moriarty, T. Fintan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Bacterial Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573441/
https://ncbi.nlm.nih.gov/pubmed/32817328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00293-20
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