HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages

Histone deacetylases (HDACs) are a group of enzymes that control histone deacetylation and bear potential to direct expression of large gene sets. We determined the effect of HDAC inhibitors (HDACi) on human monocytes and macrophages, with respect to their polarization, activation, and their capabil...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ghiboub, Mohammed, Zhao, Jing, Li Yim, Andrew Y. F., Schilderink, Ronald, Verseijden, Caroline, van Hamersveld, Patricia H. P., Duarte, Jose M., Hakvoort, Theodorus B. M., Admiraal, Iris, Harker, Nicola R., Tough, David F., Henneman, Peter, de Winther, Menno P. J., de Jonge, Wouter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573361/
https://ncbi.nlm.nih.gov/pubmed/33123128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.550769
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