HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages

Histone deacetylases (HDACs) are a group of enzymes that control histone deacetylation and bear potential to direct expression of large gene sets. We determined the effect of HDAC inhibitors (HDACi) on human monocytes and macrophages, with respect to their polarization, activation, and their capabil...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Ghiboub, Mohammed, Zhao, Jing, Li Yim, Andrew Y. F., Schilderink, Ronald, Verseijden, Caroline, van Hamersveld, Patricia H. P., Duarte, Jose M., Hakvoort, Theodorus B. M., Admiraal, Iris, Harker, Nicola R., Tough, David F., Henneman, Peter, de Winther, Menno P. J., de Jonge, Wouter J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573361/
https://ncbi.nlm.nih.gov/pubmed/33123128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.550769
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