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HIV-1 Gag protein with or without p6 specifically dimerizes on the viral RNA packaging signal

The HIV-1 Gag protein is responsible for genomic RNA (gRNA) packaging and immature viral particle assembly. Although the presence of gRNA in virions is required for viral infectivity, in its absence, Gag can assemble around cellular RNAs and form particles resembling gRNA-containing particles. When...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sarni, Samantha, Biswas, Banhi, Liu, Shuohui, Olson, Erik D., Kitzrow, Jonathan P., Rein, Alan, Wysocki, Vicki H., Musier-Forsyth, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573273/
https://ncbi.nlm.nih.gov/pubmed/32817318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014835
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