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An alternative model for type I interferon induction downstream of human TLR2

Surface-exposed Toll-like receptors (TLRs) such as TLR2 and TLR4 survey the extracellular environment for pathogens. TLR activation initiates the production of various cytokines and chemokines, including type I interferons (IFN-I). Downstream of TLR4, IFNβ secretion is only vigorously triggered in m...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Oosenbrug, Timo, van de Graaff, Michel J., Haks, Mariëlle C., van Kasteren, Sander, Ressing, Maaike E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573265/
https://ncbi.nlm.nih.gov/pubmed/32796029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015283
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