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Increased surface charge in the protein chaperone Spy enhances its anti-aggregation activity
Chaperones are essential components of the protein homeostasis network. There is a growing interest in optimizing chaperone function, but exactly how to achieve this aim is unclear. Here, using a model chaperone, the bacterial protein Spy, we demonstrate that substitutions that alter the electrostat...
Shranjeno v:
| izdano v: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7573262/ https://ncbi.nlm.nih.gov/pubmed/32817055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012300 |
| Oznake: |
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